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Bariatric Surgery effects on PCOS

Posted On : May 17, 2017

Women with Polycystic Ovary Syndrome (PCOS) often feel hopeless and depressed with their diagnosis. Bariatric Surgery improves metabolic syndrome, diabetes resolution, cardiac improvement, quality of life, and increased life expectancy. Bariatric Surgery effects on PCOS are positive in many aspects. However, there isn’t a consensus regarding recommendation for bariatric surgery for PCOS other than morbidly obesity with co-morbities.

PCOS has been shown to effect approximately 10% of women of childbearing age with symptoms of menstrual abnormalities, poly cystic ovaries, and excess androgen (male sex hormone). PCOS should be diagnosed by ensuring there are no other underlying endocrine issues. There are several associated disease processes that seem to be related to PCOS, such as Type 2 Diabetes, higher depression and anxiety, increased cardiovascular risks, stroke, hyperlipidemia, sleep apnea, overall inflammation, and endometrial cancer.

Bariatric surgery can improve several issues related to PCOS such are Type 2 Diabetes, lower weight, sleep apnea, infertility, and hyperlipidemia. Duodenal Switch has the highest rate of Type 2 Diabetes resolution of all weight loss surgeries available at this time.  Duodenal Switch also significantly improves hyperlipidemia.Weight loss surgery has been shown to improve and in some cases resolved PCOS in general. A recent meta-analysis of the effects of bariatric surgery in more than 22,000 procedures found an average weight loss of 61%, associated with the complete resolution or improvement of diabetes, hyperlipidemia, hypertension, and obstructive sleep apnea in more than 60% of the patients. Another study looked just at PCOS patients and their metabolic improvement from 47% of the PCOS population to only 21% post Bariatric Surgery. 

Several recent article have described how Bariatric Surgery effects PCOS with positive aspects related to fertility. The range of improved fertility in post Bariatric PCOS patients is a wide range of 33-100% with in the literature. It is thought that the loss of fat mass improves hormone levels and insulin resistance in PCOS and has a positive effect on fertility. One study of only 6 omen had a 100% improvement of infertility. American Society of Metabolic and Bariatric Surgery as well as the American College of Obstetricians and Gynecologist have a statement that bariatric surgery is should not be considered a treatment for infertility. The graphic below demonstrates the overlap of some of the symptomatology between PCOS, obesity and metabolic syndrome.

There are several documented positive effects and improvement in co-morbidilties related to PCOS post Bariatric Surgery. These include lipid profile, lower weight, cardiovascular risk, hypertension, and fertility. It is important to note that certain bariatric surgeries have better resolution of these co-morbidities or symptoms of PCOS. Always discuss with your physicians and surgeon what your options are and which treatments may work best for you.

In Summary, PCOS is a metabolic disease condition affecting different organ systems.  Weight loss surgery should be considered as a viable treatment option and should be discussed with your OB/GYN and Infertility specialist.

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