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Article Category: COVID-19
Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 — COVID-NET, 14 States, March 1–30, 2020
The novel coronavirus that causes coronavirus disease 2019 (COVID-19). It was first detected in December 2019. As of April 8, the date fo publication of the this article, approximately 1.3 million cases have been reported worldwide. This includes approximately 330,000 in the United States. Since this is an eveolving epidemiological condition then the information information is updated continously
Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture
Date of Publication: November 2010
Zinc ions are involved in many different cellular processes and have proven crucial for the proper folding and activity of various cellular enzymes and transcription factors.
Increasing the intracellular Zn2+ concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses, including poliovirus and influenza virus. For some viruses this effect has been attributed to interference with viral polyprotein processing.zinc_Coronavirus
Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts
Date of Publication: February 2020
Isolation of cases and contact tracing is used to control outbreaks of infectious diseases. This has been used for COVID-19. Whether this strategy will achieve control depends on characteristics of both the pathogen and the response.Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts.
Hypertension & Diabetes mellitus and COVID-19
Date of Publication: March 2020
Hypertension and Diabetes mellitus were noted to be significnat risk factor for severe COVID-19 disease and mortality. As a result, physical isolation should be take seriously.
Ocular Transmission of COVID-19
Date of Publication: February 2020
Occular transmission of COVID-19 should not be overlooked. There are not large scale data available. However from what is know, and based on the family of the viruses, all precuations should be made.
Hydroxychloroquine & Azithromycin, Possible Rx for COVID-19
Date of Publication: March 2020
Hydroxychloroquine & Azithromycin
Hydroxychloroquine and azithromycin have been tried in one small series of patients exposed to COVID-19 with mixed results. Given the potential sideffect of the medications, we should wait until medical professionals make the recommendation.
Origin and evolution of pathogenic coronavirus
Date of Publication: March 2019
How the virus travels between the animal hosts and humans. There are many pathways that cross the barrier between species resulting in the tranmission of disease.
Coronavirus disease (COVID-19): Physical activity while taking precautions
Date of Publication: January 2020
Phsycial Isolation and inactivity are not the same. It appears that the only effective tool we have agains Coronavirus is risk reduction. As a result we have all been advised to minimize social contact and in some cases stay home. We can, and should keep some level activity.
Transmission routes of 2019-nCoV and controls in dental practice
Date of Publication: March 2020
Dental Practices are not immune to Cover-19. The novel β-coronavirus (2019-nCoV) can cause severe and even fetal pneumonia. 2019-nCoV can also be transmitted through the saliva, and the fetal–oral routes may also be a potential person-to-person transmission route.
2019-nCoV epidemic: what about pregnancies?
Date of Publication: February 2020
The Coronavirus, 2019-nCoV seems to have a similar pathogenic potential as SARS-CoV and MERS- CoV. Consequently, a pregnant women may be at increased risk of severe infections. Since there are no specific early clinical signs of coronavirus exposure, it is therefore critical to minimize chance of exposure.
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